The Nerazzurri are currently third in Serie A, 11 points adrift of their opponents who have an eight-point lead at the top of the table after just 14 games.
Having won just once in 12 away games against the champions, they are 5/1 (6.00) outsiders to inflict on them the first defeat of Serie A season.
Massimiliano Allegri's men have dropped just two points from the first available 42, and are priced at just 4/7 (1.57) to equal the best ever start after 15 games by a team from Europe's top five leagues by coming out on top once again.
The sides shared a 0-0 draw when they met here in last season's respective fixture, and you can get odds of 14/5 (2.80) on them cancelling each other out.
Emre Can is hoping to rejoin the squad after returning to training following thyroid surgery, although Alex Sandro and Sami Khedira are unlikely to be fit enough to play.
Dalbert and Radja Nainggolan will both face late fitness tests after training apart from the rest of the group this week in an effort to recover from injury.
The Bianconeri's already comfortable lead is particularly impressive given the chasing pack have hardly been in sluggish form this season, with Luciano Spalletti's team having won eight of their last 10 games.
Although outsiders, they will therefore be feeling fairly confident of making a decent game of it at the Allianz Stadium, particularly given their productive form in attack.
With 21 goals to their name in their last 10 away league matches, odds of 19/20 (1.95) look generous on Inter at least joining the hosts on the scoresheet, ensuring goals at both ends for Juventus' fourth home game in five.
Odds correct at the time of writing. Please gamble responsibly.